Mulder and Scully travel to a nursing home where they discover that something unrestly is attacking people.

A nurse, Michelle enters an abandoned bedroom in a nursing home to change the sheets. Suddenly the door closes, the bed moves and she is pinned down to the bed and raped by an unseen force as her screams for help echo down the corridor.

Mulder and Scully interview Michelle who accuses one of the patients, Hal Arden of raping her as he has been making sexual gestures to her recently. She does say though that he was invisible while he did this which does put her case in a slightly more bad light and even more when Hal is just a wrinkly old man who wouldn't be able to hurt a fly. When the two agents leave, Hal secretly talks to his room-mate, Stan about taking the pill that is treating him for Alzheimer's and taking him back to his youth again. Stan warns him about taking the pill but Hal ignores this. Suddenly, Hal starts choking and Scully is unable to save him apparently being choked by an invisible hand.

One of the doctors explains that the pill is being used to treat the patients for their disease and is proving to be very effective. Later on, Stan runs off as one of the orderlies packs his bags ready for him to leave. He chases after Stan and is led out onto the roof when suddenly something unseen pushes him and lifts up his fingers from the ledge he is clinging to. Mulder tries to save him but is unable to.

As Scully talks to one of the workers at the hospital, one of the patients, Dorothy starts talking to seemingly invisible figures that are around Scully. Meanwhile, Mulder finds a room in which someone is growing mushrooms and Mulder also finds a dead body buried beneath the soil. He finds that one of the orderlies, Gung is growing the mushrooms and so Mulder talks to him. He explains that he was growing the mushrooms to use for the drug but that "something has gone terribly wrong" and that he has in fact unleashed the ghosts of former patients who are out for revenge.

When Mulder hears a scream, he rushes into a bathroom to find Michelle pinned against the wall being thrown by something invisible. As Scully rushes to see what is happening, the door closes by itself and locks. The room begins flooding with water and elsewhere in the hospital, Stan is going into a fit at the same time. Just as the water is about to fill to the top, the door bursts open and the ghosts are put to rest forever.

Gung is later sacked from the home's staff and the pill is no longer given to the patients. This makes them return to their useless state as we see Stan in the final scene, staring at nothing unable to speak....